In order to evaluate the biochemical properties of dragon’s head) Lallemantia iberica L.( ecotypes’ using some anti-perspirants in rainfed conditions in the crop year 2018 an experiment was conducted in Karaj and Khorramabad regions. The experiment was performed based on a randomized complete block design) RCBD( with a factorial arrangement consisting of three replications. The first factor consists of four different ecotypes of dragon’s head) Kurdistan, Takab, Nazarkahrizi and Kalibar( and the second factor were included three anti-transpirant compounds )kaolin with a concentration of 5 Percent, chitosan with a concentration of 1 Percent and Ista with a concentration of 2 Percent( and no anti-transpirant )control(. The results showed that using anti-transpirants increased the amount of the activity of catalase and peroxidase enzymes. Ista anti-transpirant had a greater effect on enzyme activity than kaolin and chitosan. The highest amount of peroxidase and catalase )0.51-0.39 unit mg /protein( were obtained respectively from the ecotypes of Kurdistan treated with Ista and in Karaj cultivation. In addition, the highest grain yield and biomass yield were obtained from treatment with chitosan, which increased (4-20%) compared to the control, respectively. Based on the results, using anti-transpirants in dryland cultivation conditions improved most of the studied yield traits and biochemical traits compared to the control.