One of the most important pathogens in plants including pomegranate, are root-knot nematodes (Meloidogyne spp.) causing considerable damage to this important export product. Due to the importance of the subject which was done in 2018- 2019 in the Faculty of Agriculture of Lorestan University, studies with treatments including organic fertilizer (40, 60 and 80 t/ha.), vermicompost (40 t/ha.) and Marygld product (200, 300 and 400 g/m2) were done in a completely random design on the dominant root-knot nematodes species, M. javanica under greenhouse conditions on pomegranate seedlings. The measurement indicators included gall index, the number of egg sacs and the final population of egg and J2 larvae in the soil and the roots, and growth factors of pomegranate seedlings. Reproduction factor and the percentage of increase or decrease of root knot nematode population, were calculated in each treatment compared to the initial population of the same treatment. The results showed vermicompost (40 t/ha.) with 94.35 percent reduction in population of egg and larvae had the highest effect on reducing the nematode population compared to the other treatments. Marygld 400, 300 and 200 g/m2 treatments were ranked next by 93.47, 91.21 and 92.65 percent reduction in nematode population respectively and then the nematode reduction in the composts of 80, 60 and 40 t/ha by 89.67, 86.55 and 86.81 percent respectively.