This study was carried out to assess yield, yield components and quality traits of dragon’s head )Lallemantia iberica L. ( ecotypes’ seeds grown using some anti-transpirant agents in rainfed system in two regions of Iran inc luding Karaj & Khorramabad in 2018. The experiment was performed based on a randomized complete block design (RCBD)with a 4*3 factorial arrangement consisting of three replications. The first factor consists of four different ecotypes of dragon’s head)Kurdistan, Takab, Nazarkahrizi and Kalibar) and the second factor including three anti-transpirant compounds (kaolin with a concentration of 5 Percent, chitosan with a concentration of 1 Percent and Ista with a concentration of 2 Percent) and no anti-transpirant(control).The results indicated that the triple interaction of ecotypes, anti-transpirant and location on most of the studied traits was significant. Among anti-transpirant, chitosan had the greatest effect on cultivated ecotype & increased grain, biomass, oil and mucilage yields by 20, 4, 11, 18 Percent, respectively. Also, Nazarkahrizi, Kalibar, Kurdistan and Takab ecotypes cultivated in Karaj had the highest values in the studied traits under foliar application with anti-transpirant, respectively. According to the studies conducted in this study, the selection of a suitable ecotypes with the region and the use of antiperspirants improve the yield & yield components, quality traits of dragon’s head in rainfed cultivation conditions.