In order to evaluation of some morphological and chemical characteristics of quinoa, split plot experiment was conducted in a randomized complete block design with three replications 2019-2020 cropping season, at the Agricultural Research station of University of Zabol, Iran. Vermicompost at three levels (0, 5 and 10 ton/ha) considered as main factor and chemical fertilizer at four levels (25, 50, 75 and 100%) considered as sub-factor. The main effect of vermicompost was significant on morphological traits such as plant height, 1000-seed weight, biological yield, grain yield and harvest index. Interaction of vermicompost and chemical fertilizer was significant on chemical properties including proteins and photosynthetic pigments. Application of 10 tons of vermicompost per hectare led to the maximum level of plant height, 1000-seed weight, biological yield, grain yield and harvest index. Also, the highest amounts of photosynthetic proteins and pigments were achieved from combined application of 10 tons/ha of vermicompost and 50% chemical fertilizer (25 kg/ha Urea + 50 kg/ha triple superphosphate + 50 kg/ha potassium sulfate). Totally, results showed the positive effects of vermicompost on the morphological and chemical properties of quinoa. It can be concluded that the combined use of chemical fertilizers and vermicompost can increase the yield of quinoa while reducing the use of chemical fertilizers and thus reduce the environmental impacts caused by them.